Gene Editing Services in Saccharomyces

Saccharomyces includes many species of yeasts considered very important in food industry, such as S. cerevisiae also known as baker's yeast or brewer's yeast. As a simple eukaryotic cell, they serve as model of all eukaryotes, including human being.

Lifeasible offers gene editing services in the well-studied yeast Saccharomyces, aiming at assisting global customers make great breakthroughs in their fields.

Overview of Saccharomyces

Saccharomyces is a genus of fungi with many species of yeast included. They are widely used in food production, such as brewing ethanol beverages and baking bread. The life cycle of S. cerevisiae contains both haploid and diploid. But natural polyploid cells can frequently be found. On one hand, polyploidization is likely to provide benefit to them, like enhancing metabolism, improving resistance of stresses and so on. On the other hand, polyploidization might affect cell philosophy which might be detrimental for cells. Some other strains of Saccharomyces, like those used in brewing, are polyploidy.

Typical Strains of Saccharomyces

• Saccharomyces cerevisiae
  S. cerevisiae is also called baker's yeast and brewer's yeast, which is used in food industry like alcoholic beverage brewing and bread baking. And it's one of the intensively studied eukaryotic model organisms in molecular and cell biology. There are many proteins important to human biology first found in S. cerevisiae, including signaling proteins, protein-processing enzymes and other proteins involved in cellular activities.
• Saccharomyces pastorianus
  S. pastorianus is the yeast used for producing lager beer, which is considered as an interspecific hybrid yeast strains. And it's one of the most important industrial organisms as well. This group of organism has strong fermentative ability, that is, it requires low temperature compared to other fermentative processes. Its allopolyploid hybrid genome may have contributed to its rapid revolution of tolerance to environment.
• Saccharomyces eubayanus
  S. eubayanus is a cryotolerant type of yeast, which is most likely to be the parent of S. pastorianus. It consists of two distinct lineages. One is allotriploid with one copy of S. cerevisiae genome and two copies of the S. eubayanus genome. Another type is allotetraploid with one full diploid genome copy of S. cerevisiae and S. eubayanus.

Our Services

Lifeasible provides gene editing services in Saccharomyces for assisting researchers studying mechanism of all vital activities in eukaryotic organisms, including gene knock-in and gene knock-out services. Our experienced scientists dedicate to provide trustable and satisfying services for our customers.  

Gene Knock-out Services in Saccharomyces

• Single Gene Knock-out Services

In order to assist our global customers understanding the regulatory mechanism of reactions happen in chloroplast of Saccharomyces, Lifeasible provide site-specific gene knock-out services.

• Markerless Multiple Gene Knock-out Services

Lifeasible provides our customers multiple gene knock-out services in Saccharomyces for studying gene-gene interaction and redundant gene function. Our scientists established a robust toolkit of multiple site-specific recombinases for implementing markerless multiple gene knock-out.

Gene Knock-in Services in Chloroplast of Saccharomyces

We offer gene knock-in service in Saccharomyces for assisting customers who need overexpressed or knocked-in strains for further research.

Service Process

Advantages

Lifeasible offers our customers innovative, efficient, customer-tailored and high-quality gene editing services. And we promise to deliver the results and products on time and with high quality. We serve researchers all over the world with heart and soul. Please feel free to contact us.