Catalog Number: RNPP-74352650
| Gene ID: | PP7435_Chr2-1077 |
| Gene Name: | RRM3 |
| Gene Location: | chr2: 1962269..1964344 |
| DNA Length (bp): | 2076 |
| Protein Length (aa): | 691 |
| Gene Description: |
ATP-dependent DNA helicase RRM3 (EC 3.6.4.12) (rDNA recombination mutation protein 3) 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability Plays also a role in mtDNA replication Has G-quadruplex (G4) unwinding activity and can suppress G4-induced genome instability when PIF1 levels are low |
| Medium: |
YPD + 1M Sorbitol broth 30% glycerol |
| Shipping condition: | Frozen Gel Packs |
| Storage condition/Stability: |
-80℃/At least 12 months 4°C/Up to 1 week |
| Hazardous: | No |
Disclaimer
This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.
