Catalog Number: RNSS-4744060
| Gene ID: | YLR442C |
| Gene Name: | SIR3 |
| Gene Location: | Chr XII: 1019315..1022251 |
| DNA Length (bp): | 2935 |
| Protein Length (aa): | 979 |
| Gene Description: |
Silencing protein Interacts with Sir2p, Sir4p, and histone H3/H4 tails to establish transcriptionally silent chromatin Required for spreading of silenced chromatin Recruited to chromatin through interaction with Rap1p C-terminus assumes variant winged helix-turn-helix (wH) fold that mediates homodimerization, which is critical for holo-SIR complex loading Required for telomere hypercluster formation in quiescent yeast cells Has paralog ORC1 from whole genome duplication |
| Medium: |
YPD broth with G418 (200 µg/mL) 15% glycerol |
| Shipping condition: | Frozen Gel Packs |
| Storage condition/Stability: |
-80℃/At least 12 months 4°C/Up to 1 week |
| Hazardous: | No |
Disclaimer
This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.