Catalog Number: RNSS-4742882
| Gene ID: | YGR184C |
| Gene Name: | UBR1 |
| Gene Location: | Chr VII: 859901..865753 |
| DNA Length (bp): | 5851 |
| Protein Length (aa): | 1951 |
| Gene Description: |
E3 Ub-ligase (N-recognin) Recognizes and ubiquitinates N-end rule pathway substrates in complex with Rad6p Roq1p-bound form accelerates degradation of misfolded and native ER membrane and cytosolic proteins as part of the stress-induced homeostatically regulated protein degradation (SHRED) pathway Role in ER-associated protein degradation Modifies Cup9p to regulate peptide transport Mutation in human UBR1 causes Johansson-Blizzard Syndrome (JBS) |
| Medium: |
YPD broth with G418 (200 µg/mL) 15% glycerol |
| Shipping condition: | Frozen Gel Packs |
| Storage condition/Stability: |
-80℃/At least 12 months 4°C/Up to 1 week |
| Hazardous: | No |
Disclaimer
This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.
