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Insect Pan-Genome Services

Insect Pan-Genome Services

The pan-genome refers to the complete set of genes possessed by all individuals within a species or taxonomic group, encompassing both core genes and variable genes. In insect research, the construction of a pan-genome facilitates the understanding of genetic diversity, adaptive evolution, and the genetic basis of artificial selection within a species. Lifeasible is committed to providing advanced technical support and comprehensive solutions for insect research. Our insect pan-genome services enable comprehensive analysis of insect genomes, helping researchers further uncover genetic diversity within species, understand insect genetic characteristics, and delve deeper into insect-related research.

What Can We Offer?

Our insect pan-genome services include a range of technologies and solutions for constructing and analyzing insect pan-genomes, helping researchers gain a deeper understanding of the genetic diversity, evolutionary mechanisms, and environmental adaptability of insect species.

High- throughput sequencing and data output
  • Short-read sequencing.
  • Long-read sequencing.
  • Transcriptome data.
  • Hi-C assisted genome assembly.
Genome assembly and evaluation
  • Pan-genome construction.
  • Multi-software assembly.
  • Evaluation of assembly results.
Pan-genome construction Compare multiple individual genomes against a reference genome, identify structural variations, and consolidate variant information across multiple samples.
Variant detection and functional annotation
  • Identify present/absent variants (PAVs), insertions/deletions, etc.
  • Functional annotation.
Biological question resolution
  • Further analysis of population structure, phylogenetics, and evolutionary dynamics.
  • Core gene and non-core gene analysis, structural variation analysis in non-core gene regions, and gene family clustering analysis.
  • Systematic evolution analysis, functional gene mapping in populations, and database deployment.

Application Areas

  • Artificial selection and breeding improvement. For example, in silkworm research, high-resolution pan-genomes were constructed through long-read sequencing of hundreds of silkworm individuals, revealing key genes associated with economic traits such as silk yield and fineness.
  • Ecological adaptation and invasion mechanisms. Pan-genome analysis has revealed genetic variation in invasive insects (such as Halyomorpha halys) related to pesticide resistance and sensory perception, aiding in understanding the reasons for their successful spread.
  • Convergent evolution studies. In the genus Nymphalidae butterflies, pan-genome analysis combined with multiple sequencing techniques has revealed the genetic regulatory mechanisms underlying the convergent evolution of wing color patterns among different species, identifying key regulatory elements (CREs).

Our Testing Process

Our service workflow.Fig.2 Our experimental process. (Lifeasible)

Why Choose Us?

  • We specialize in insect genome sequencing and have extensive experience in insect genome assembly services.
  • The Hi-C chromatin conformation capture technology libraries we provide have a high proportion of effective data and high mounting efficiency. We also have extensive experience in insect research.
  • We can integrate Hi-C with pan-genome structural variation studies to further accurately identify genomic structural variations.
  • We can process thousands of individual samples simultaneously and provide a one-stop solution.

Lifeasible provides comprehensive, multi-level services. We can help customers systematically construct, analyze, and apply insect pan-genomes, providing solid data support and technical assurance for insect genetic diversity research, breeding improvement, resistance mechanism exploration, and synthetic biology applications. If you are interested, please feel free to contact us.

For research or industrial raw materials, not for personal medical use!
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