Insect Targeted Metabolomics

As an important component of ecosystems, insects play a crucial role in ecological processes. A thorough analysis of metabolic changes within insects not only reveals the metabolic regulatory mechanisms of insects under various conditions but also provides a scientific basis for agricultural pest control, the development of new biological pesticides, and the utilization of insect biological resources. Lifeasible is committed to providing reliable and advanced solutions for insect-targeted metabolomics, thereby advancing research in the field of entomology. The insect-targeted metabolomics we offer can perform qualitative and quantitative detection and analysis of a specific metabolite, representing a biased detection method with characteristics such as high specificity, high detection sensitivity, and accurate quantification.

What Can We Offer?

Metabolite target screening and design

Based on the experimental objectives (such as stress response, nutrient metabolism, signaling molecule analysis, etc.), we assist customers in developing and optimizing target metabolite lists. We mine potential biomarkers from databases, literature, and omics data to construct personalized target profiles.

Sample preparation and extraction

Design efficient and reproducible metabolite extraction protocols for insect samples (e.g., whole insects, tissue sections, hemolymph, digestive fluids, etc.).

Quantitative analysis

Utilize liquid chromatography–mass spectrometry (LC–MS/MS) quantitative analysis and gas chromatography–mass spectrometry (GC–MS) quantitative analysis.

Data processing and statistical analysis

We provide high-quality data processing, a variety of statistical analysis methods, and visual reports to help customers quickly gain insight into metabolite change patterns.

Biological function annotation and pathway enrichment analysis

We use multiple databases to annotate the functions of differential metabolites. Combined with pathway enrichment analysis, we explore the regulatory mechanisms of key metabolic pathways.

Process of testing. Fig.2 Our experimental process. (Lifeasible)

Quantitative Analysis of Metabolites

Quantitative analysis of specific categories of metabolites	Amino acids and their metabolites. For example, tyrosine, phenylalanine, and other amino acids are involved in protein metabolism and hormone synthesis. Organic acids and their derivatives. For example, citric acid, malic acid, succinic acid, and other organic acids involved in energy metabolism. Fatty acids and lipids. Including short-chain fatty acids, glycerophospholipids, long-chain fatty acids, etc., are involved in energy storage and cell membrane structure. Nucleotides and their metabolites. Such as purines, pyrimidines, etc., related to nucleic acid metabolism and energy transfer. Plant secondary metabolites (PSMs) and their derivatives. Examples include desulfurized metabolites of sinigrin and nitriles, used to study insect detoxification mechanisms against plant toxins.
Specific detection targets	Hormones and signaling molecules. Examples include insect hormones and their synthetic precursors. Energy metabolism-related substances. Examples include glycolysis products and tricarboxylic acid cycle intermediates. Detoxification pathway metabolites. Examples include tryptophan degradation metabolites produced by insects when resisting insecticides. Immune-related metabolites. Examples include arachidonic acid metabolites and antimicrobial peptide precursors.
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Application Areas of Insect Targeted Metabolomics

Environmental stress research. Analyze the effects of temperature stress, toxin exposure, and other factors on insect metabolic adaptability and screen for stress biomarkers.
Insect-microbe interactions. Combining microbiomics to investigate the regulatory mechanisms of gut microbiota on host metabolism.
Analysis of resistance mechanisms. Targeting the quantitative analysis of pesticide metabolites to reveal detoxification pathways.
Food and feed safety. Establishing an insect product metabolism database and developing food safety standards.

Why Choose Us?

Professional technical platform and team. Our technical team has access to internationally leading LC-MS/MS and GC-MS instruments and has extensive experience in insect sample processing. They also possess extensive research experience in insect physiology, ecology, and metabolomics.
Strict quality control system. Our services use multiple quality control strategies to ensure data reliability. In addition, we have established a comprehensive SOP process that covers the entire process from sample receipt, processing, and analysis to report generation.
Personalized and high-throughput testing. We can flexibly design small-scale quantitative analysis of multiple targets or large-scale high-throughput analysis of hundreds of targets to meet the different research needs of our customers. This helps our customers save time and costs.
Comprehensive after-sales service. We provide professional data interpretation reports to help our customers understand the biological significance behind metabolic changes. We also provide follow-up technical support according to customer requirements.

Lifeasible is at the forefront of the industry in insect research and services. We focus on cutting-edge technologies in insect research, continuously optimizing and updating our technical systems. To date, we have completed dozens of insect-targeted metabolomics projects, covering areas such as pest physiology and ecology, beneficial insect farming, and insect resource development. If you are interested, please feel free to contact us.

For research or industrial raw materials, not for personal medical use!

Services

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