T2T (Telomere-to-Telomere) genome assembly refers to gap-free, high-quality assembly spanning from telomere to telomere. Multi-platform high-depth sequencing combined with algorithmic integration has overcome challenges in highly repetitive regions such as telomeres and centromeres, facilitating in-depth species research. Lifeasible focuses on the field of insect research. We provide insect T2T genome assembly, which enables complete, high-quality assembly of chromosomes from telomere to telomere. For insects, a complex and diverse group, T2T assembly can help comprehensively reveal their genome structure, functional components, evolutionary mechanisms, and adaptive characteristics.
| Insect genome T2T sequencing and assembly | Provides complete chromosome sequence construction covering telomere to telomere. High-quality assembly including complex repetitive sequence regions and centromere regions. |
| Identification of highly repetitive regions and structural variations | Accurate analysis of large fragment repetitive sequences and structural variations (SV). Identification and functional annotation of centromere and telomere sequences. |
| High-precision annotation services | Prediction of protein-coding genes. Identification of non-coding RNAs (such as tRNA, rRNA, miRNA, etc.). Classification and annotation of transposable elements and repetitive sequences. |
| Population comparison and evolutionary analysis | T2T genome construction and comparative analysis of multiple insect samples. In-depth study of population structure, selective pressure, and phylogenetic evolution. |
| Downstream data integration services | Integration with multi-omics data such as transcriptomics, epigenomics, and metabolomics. Comprehensive interpretation including gene function analysis and pathway enrichment analysis. |
Fig.2 Our experimental process. (Lifeasible)
Lifeasible relies on advanced sequencing platforms and comprehensive bioinformatics analysis capabilities to provide high-quality insect T2T genome services, helping scientific research institutions, agriculture, medicine, and bioindustry customers achieve higher-level genome research goals. If you are interested, please feel free to contact us.