Name: Quinolinic acid
SKU: ALK-0023

Cat#

ALK-0023

Product Name

Quinolinic acid

CAS No.

89-00-9

Description

Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction.

Structural Formula

Quinolinic acid

MW

167.12

MF

C7H5NO4

Purity

0.9981

Appearance

Solid

Solubility

DMSO : 33.33 mg/mL(199.44 mM;Need ultrasonic) H2O : 3.33 mg/mL(19.93 mM;Need ultrasonic)

Storage

-20℃ for 3 years

IC50 & Target

Topoisomerase I

Shipping

Room temperature in continental US; may vary elsewhere.

SMILES

O=C(C1=NC=CC=C1C(O)=O)O

In Vitro

Quinolinic acid (0-50 mM; 24 hours) decreases the percentage of survival cells ranging from 100±0.01% at 5 mM to 45.23±0.01% at 50 mM in N18D3 cells.

Datasheet