Silk and Spider Silk Development

Lifeasible provides product development services for both silk and spider silk by modifying the properties of silk proteins, such as blending with polymers, chemical modification, etc., to obtain silk protein products with different properties. For spider silk proteins, we offer the development of recombinant spider silk proteins and the development of protein expression in different types of vectors. Our professional staff will provide you with the best product development services and exclusive solutions for your projects.

Background

Silk and spider silk have excellent mechanical properties, biocompatibility, and degradability. Both silk protein fibers and spider silk proteins are natural materials with multi-level structures, and the excellent combined mechanical properties of both are inextricably linked to their multi-level structures. The seemingly smooth surfaces of silk and spider silk proteins fibers are composed of many oriented nanofiber bundles, which have a fishing net-like structure composed of β-folded crystals and amorphous proteins interconnected. β-folded crystals act as nodes carrying stress in the fishing net-like structure, while amorphous proteins like a rope connect one node (β-folded crystal) to another, forming a structure that is both flexible and strong.

Fig.1 The hierarchical structure of Bombyxmori silkworm and Nephilapilipes spider dragline silk fibers. (Nguyen et al., 2015)

Our Services

• Silk Fibroin Nanofibers Development

We provide high-quality product development services such as property modification and structural design of silk fibroin proteins.

• Spider Silk Fiber Development

We provide our customers with expertise in developing spider silk fibers. We specialize in bioengineering methods, i.e., transferring spider silk protein genes into other organisms to express silk proteins and then artificially spinning the silk. The vectors include mammals, silkworms, plants, microorganisms, etc.

• Recombinant Spider Silk Proteins Development

By obtaining recombinant silk proteins through heterologous expression, Lifeasible can provide customers with recombinant spider silk protein development services, including spider silk protein expression and purification, design and construction, and modification of spider silk proteins finally the preparation of nanofibers by using spinning technology.

If you are interested in our services, or if you want a service not listed above, please feel free to contact us, and our staff will customize a professional product solution for you.