The endoplasmic reticulum (ER) has long been recognized as a highly dynamic and pleomorphic organelle. The ER structure resembles a spider web network of interconnected tubules and pools throughout the cell. It is a continuous membrane system consisting of a slippery endoplasmic reticulum and a rough endoplasmic reticulum with ribosomes attached. In plant cells, it is responsible for the synthesis of one-third of the cellular proteome; it produces hormone receptors and transporters and proteins responsible for the biosynthesis of critical components of the cellulose cell wall.
Lifeasible, as a leading plant biotechnology company, is committed to helping our customers achieve effective and successful research. We provide extraction and purification of ER in plants, as well as varieties analyses, including structure, function, stress response, and mechanism. In addition, we deliver reliable results and reports on time to our customers worldwide.
The plant endoplasmic reticulum is where protein transport, modification, and metabolism occur, including folding, refolding, degradation and secretion. The ER is a complex, intricate network of interconnected membrane channels and lamellae that are inevitably damaged even during the mildest and most transient cellular homogenization. We provide a variety of methods for ER isolation, purification, and proteomic studies to facilitate further study for customers.
Since the first visualization of ER networks in living cells using fluorescent dyes, the advent of fluorescent protein technology and advanced quantitative imaging techniques in living cells has made significant progress in understanding the conserved and plant-unique mechanisms underlying ER structure and dynamics. We provide plant endoplasmic reticulum structure observation, remodeling, and protein localization analysis to better study the structure of the endoplasmic reticulum.
The ER is the second largest organelle after mitochondria. It forms a series of interconnected flat tubular tunnels or sacs, including the rough endoplasmic reticulum (RER) and smooth endoplasmic reticulum (SER), which are mainly responsible for the maintenance and transport of proteins formed in the ribosome. We provide functional analysis of plant endoplasmic reticulum proteins and related gene analysis to facilitate the studies of molecular mechanisms.
The endoplasmic reticulum of plant cells differentiates many kinds of cellular structures, mainly in storing a large number of proteins synthesized by the endoplasmic reticulum. There are two types of endoplasmic reticulum-derived structural inclusions, such as the precursor-accumulator (PAC) vesicle, protein body, and MAIGO2 (MAG2) body, which contain a large number of storage proteins. In addition, ER body and HDEL vesicle contain a large number of hydrolases. Each of these structures has a distinct function, and we provide a functional analysis of the different structures derived from the ER.
Under adverse environmental conditions, the accumulation of misfolded proteins in the ER of plants can cause ER stress and induce unfolded protein responses. However, the stress response mechanism of ER can alleviate the damage caused by biotic or abiotic stress and improve plant stress tolerance. We mainly provide analysis of pathways to re-achieve ER homeostasis, including non-folded protein responses, ER-related protein degradation processes, autophagy processes, and apoptosis.
Recent studies have shown that ER also plays an important role in signal transduction and integration in response to biotic and abiotic stresses, such as salt stress, heat stress, and others. We provide different biotechnology methods, and ideas to explore the regulatory relationship between salt stress and ER.
If ER stress persists and cannot be reversed, prolonged stress can lead to cellular dysfunction, activating cell death signals as the ultimate survival attempt. Increasing evidence indicates that ER stress-induced cell death signaling pathway is an important contributor to plant stress adaptation. We provide an analysis of the mechanisms involved in this process.
Lifeasible is always devoted to providing high-quality and satisfactory service to our customers. If you are interested in our services or have any questions, please feel free to contact us or make an online inquiry.
Lifeasible has established a one-stop service platform for plants. In addition to obtaining customized solutions for plant genetic engineering, customers can also conduct follow-up analysis and research on plants through our analysis platform. The analytical services we provide include but are not limited to the following: