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Nicotinic acid riboside

Nicotinic acid riboside

Cat#
ALK-0027
Product Name
Nicotinic acid riboside
CAS No.
17720-18-2
Description
Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism.
Structural Formula
Nicotinic acid riboside
MW
255.22
MF
C11H13NO6
Purity
0.9806
Appearance
Solid
Solubility
H2O : 62.5 mg/mL(244.89 mM;Need ultrasonic)
Source
Plants >Agrostidoideae > Triticum aestivumL.
Storage
-20℃ for 3 years
IC50 & Target
CYP1
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
[O-]C(C1=C[N+]([C@@H]2O[C@@H]([C@H]([C@H]2O)O)CO)=CC=C1)=O
In Vitro
Nicotinic acid riboside (HepG2 cells; 0.01 nM~0.1 mM) helps FK866-treated cells to maintain viability at low micromolar concentrations. Nicotinic acid riboside formation and release are caused by overexpression of FLAG-tagged CN-II and CN-III in HEK293 and HepG2 cells. CN-II and CN-III generate Nicotinic acid riboside in vitro by dephosphorylation of nicotinic acid mononucleotide (NAMN).
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