Name: Nicotinic acid riboside
SKU: ALK-0027

Cat#

ALK-0027

Product Name

Nicotinic acid riboside

CAS No.

17720-18-2

Description

Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism.

Structural Formula

Nicotinic acid riboside

MW

255.22

MF

C11H13NO6

Purity

0.9806

Appearance

Solid

Solubility

H2O : 62.5 mg/mL(244.89 mM;Need ultrasonic)

Source

Plants >Agrostidoideae > Triticum aestivumL.

Storage

-20℃ for 3 years

IC50 & Target

CYP1

Shipping

Room temperature in continental US; may vary elsewhere.

SMILES

[O-]C(C1=C[N+]([C@@H]2O[C@@H]([C@H]([C@H]2O)O)CO)=CC=C1)=O

In Vitro

Nicotinic acid riboside (HepG2 cells; 0.01 nM~0.1 mM) helps FK866-treated cells to maintain viability at low micromolar concentrations. Nicotinic acid riboside formation and release are caused by overexpression of FLAG-tagged CN-II and CN-III in HEK293 and HepG2 cells. CN-II and CN-III generate Nicotinic acid riboside in vitro by dephosphorylation of nicotinic acid mononucleotide (NAMN).

Datasheet