Kifunensine

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Cat#

ALK-0061

Product Name

Kifunensine

CAS No.

109944-15-2

Synonyms

FR-900494

Description

Kifunensine, a potent and selective inhibitor of class I α-mannosidases isolated from Actinomycete, prevents α-mannosidases I from trimming mannose residues on glycoproteins. Kifunensine inhibits ERAD.

Structural Formula

Kifunensine

232.19

C8H12N2O6

Purity

0.993

Appearance

Solid

Solubility

DMSO : 11.9 mg/mL(51.25 mM;Need ultrasonic)

Source

actinomycete

Storage

-20℃ for 3 years

IC50 & Target

Plasmodium

Shipping

Room temperature in continental US; may vary elsewhere.

SMILES

O=C(N1[C@@](N2)([H])[C@@H](O)[C@@H](O)[C@H](O)[C@H]1CO)C2=O

In Vitro

Kifunensine, an alkaloid from actinomycete Kitasatosporia kifunense 9482, is the most efficient nhibitor of a-mannosidase I, blocking N-glycan synthesis at an8GlcNAc2 (Man8) or Man9GlcNAc2 (Man9) stage.

Datasheet

Our products/services are For Research Use Only. Not For Clinical Use!

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