Product Name
Ifenprodil tartrate
Description
Ifenprodil tartrate is a typical noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM). Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has the potential to be a cerebral vasodilator.
Structural Formula
Ifenprodil tartrate
Solubility
DMSO : ≥ 500 mg/mL(1248.47 mM ) H2O : 5 mg/mL(12.48 mM;Need ultrasonic)
Source
Plants >Crassulaceae > Sedum sarmentosumBunge
Storage
4℃, sealed storage, away from moisture
IC50 & Target
Topoisomerase I
Shipping
Room temperature in continental US; may vary elsewhere.
SMILES
OC(C1=CC=C(O)C=C1)C(C)N(CC2)CCC2CC3=CC=CC=C3.O=C(O)[C@H](O)[C@@H](O)C(O)=O.[1/2]
In Vitro
G protein-activated inwardly rectifying K+ channels (GIRK).
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Datasheet 