Microalgal Genomics

The advent of the omics era has revolutionized the study of microalgal biology. More than 100 whole genome sequences from algae have been published or are about to be published. Genome-scale studies of microalgae can provide in-depth information on intracellular metabolism from a global scale and facilitate the development of robust microalgal strains and efficient processes. Here, Lifeasible provides professional solutions for microalgal genomics.

Microalgal Genomics

Microalgae are widely studied for biofuel production and greenhouse gas emission reduction. In addition, microalgae are producers of a variety of high-value biochemicals and are a renewable and sustainable energy source with potential for development. With the rise of next-generation sequencing (NGS) technology, important genomic data on microalgae have been obtained. Access to genomic data is playing an increasing role in biotechnology. The rapid increase in these genetic data is changing our understanding of one of the most diverse, complex, and understudied groups of photosynthetic eukaryotes. Genome sequencing, phylogenomics, and functional genomics can unlock the functional potential of individual algae. Therefore, research on sequencing and annotation of microalgal genomes is receiving increasing attention.

Fig 1. Genome editing and synthetic biology applications in metabolic engineering of microalgae and cyanobacteria. (Ng I S, et al., 2020)

Customized Solutions

With more than half of the proteins encoded by algal genomes having unknown functions, developing convenient genome editing tools is key to elucidating relevant details of microalgal metabolism and developing targeted variants with desired traits. Lifeasible is committed to large-scale whole-genome sequencing of locally isolated and selected microalgae and macroalgae to define their genome-encoded DNA components. We offer microalgae genomics, including but not limited to:

• Analysis of Microalgal Genomic Features
• Comparative and Functional Microalgae Genomics
• Synthetic Biology of Genetic Microalgae
• Genome Editing in Microalgae Through CRISPR Technology
• Microalgae Mitochondrial Genomics
• Microalgae Chloroplast Genomics

We offer not only whole genome sequence information sequencing of model representative algae from other classes, such as cyanobacteria, blue-green algae, red algae, and brown algae but also comparative genomics between different microalgal groups to identify genomic features such as gene order, DNA regulatory sequences, and other genomic structural signatures. We aim to quickly solve your microalgae genomics problems by expanding the available gene sequences by a factor of 20 while having equal representation from multiple microalgal species.

Our Available Techniques

• Microalgae gene platform.
• DNA synthesis technology.
• Annotate the genome.
• Feature synthesis toolbox.
• Precise genome editing tools, including microarrays, antibodies, RNA interference (RNAi), and genetic transformation.
• Gene-protein response method.

At Lifeasible, our genomics services for microalgae allow us to design these organisms in a more competent manner, resulting in better carbon partitioning capabilities, high titer biocompound production, and better genetic stability. We are your trusted partner in all aspects of microalgae research. If you are interested in our solutions for microalgae genomics, please do not hesitate to contact us.