Targeted metabolomics aims at measuring previously defined groups of chemically characterized and biochemically annotated metabolites, such as metabolic intermediates, hormones and other signaling molecules, and secondary metabolites. Compared to untargeted metabolomics, targeted metabolomics provides better quantitation and validation with the help of internal standards and specific mass spectrometer conditions. Targeted metabolomics has been an emerging technology that holds promise to inform the practice of precision breeding and disease therapy.
Lifeasible has developed state-of-the-art platforms for targeted metabolomics analysis in animal. Our targeted metabolomics platforms have characteristics of high accuracy, specificity, and sensitivity. We have robust and comprehensive capabilities for both targeted metabolomic pathways and targeted metabolites (Table 1).
Table1. List of Targeted Metabolites Analysis Services
|Targeted Metabolomic Pathways||Carbohydrates & Glycolysis Pathways, TCA Cycle, Pentose Phosphate Pathway, Mevalonate Pathway, Methionine Cycle, Isoprenoid Biosynthesis, Carnitine Biosynthesis, Pyrimidine Biosynthesis, Tryptophan Metabolism, etc..|
|Organic Compounds||Acyl CoAs, Aldehydes, Carnitines, Amino Acid, Nucleotides, Thiols, Bioamine, Flax-Lignans, Oxysterols, Vitamins & Coenzymes, Animal Hormones, Bile Acids, Fatty Acids, Organic Acids, neurotransmitter, Ceramides, Plasmalogens, Biliverdin Isomers, Ubiquinone, Cholestanol, etc..|
|Inorganic Compounds||Metal/Metallomics, etc..|
We guarantee accurate analysis of targeted metabolites, even in low abundance, employing mainly two analytical techniques. These technologies are based on nuclear magnetic resonance (NMR) spectroscopy, and mass spectrometry (MS) coupled to either gas chromatography (GC) or liquid chromatography (LC). We also offer univariate and multivariate statistical analysis to unravel the hidden information contained in the collected data. Our skilled experts will work closely with you through every step of your project, providing optimized protocols from sample preparation to data analysis. Welcome to contact us for details on collaborations and pricing.