Untargeted Metabolomics Analysis in Animal

Untargeted Metabolomics Analysis in Animal

Untargeted metabolomics, namely discovery metabolomics, is an intended comprehensive analysis of all the measurable analytes in a sample including chemical unknowns. These analytes are small molecules and usually include sugars, lipids, amino acids, fatty acids, phenolic compounds, alkaloids, and many more. As a high-throughput technology, untargeted metabolomics provides a powerful approach to early phase diagnosis and discovery of new biomarkers in a great extent. Importantly, untargeted metabolomics allows more comprehensive analysis with more accurate data acquisition, eliminating biased research direction.

Lifeasible, as a leading biotechnology company, offers high-quality untargeted metabolomics analysis service in animal. We leverage our experience, expertise, and technologies to advance the forefront of untargeted metabolomics analysis in animal.

The experimental workflow of untargeted metabolomics analysis involves 5 steps (Figure 1):

  • Sample collection and extraction.
  • Data collection.
  • Data analysis.
  • Identification of known metabolites.
  • Characterization of unknowns.

Figure 1. Overall workflow for an untargeted metabolomics analysis (Vinayavekhin  and Saghatelian, 2010)Figure 1. Overall workflow for an untargeted metabolomics analysis (Vinayavekhin and Saghatelian, 2010)

With years of experience in biochemistry and statistics analysis, Lifeasible offers customized one-stop services for untargeted metabolomics analysis in animal including all steps described above (Figure 1). We provide optimal protocols to guarantee data with high accuracy, specificity, and sensitivity using advanced technologies and statistical methods. These technologies include liquid chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometry (GC-MS), and nuclear magnetic resonance (NMR). Our experts are also skillfully in a variety of software packages for the analysis of metabolomics data. Welcome to contact us to find out how your business can benefit from our animal untargeted metabolomics analysis service.

Reference

  1. Vinayavekhin N.; Saghatelian A. Untargeted metabolomics. Current protocols in molecular biology. 2010, 30.1.1-30.1.24.
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